Neural Blockades.
Nerves that conduct the sensation of pain can be blocked temporarily or
permanently. Temporary nerve blocks use local anesthesia. Permanent blocks
actually destroy nerves with heat, cold, alcohol or phenol. A local anesthetic
block often is performed first so that a physician can gauge the approximate
impact of the permanent block, and the patient can judge whether other
effects—usually numbness—are tolerable. Sometimes, temporary blocks are used
for intermittent relief, although this is less common in cancer pain.
Neurolytic Blocks. This approach stops the nerves' transmission of
pain signals for a prolonged period of time. Although these blocks are called
permanent, nerves can regenerate and cause pain again. For this reason, the
relief to be gained from neurolytic blocks should be balanced against a person's
life expectancy. There are several types of neurolytic blocks:
- Peripheral nerve blocks are most commonly done on patients who
have localized pain due to tumor invasion into the surrounding tissues
innervated by the affected nerve.
- Sympathetic nerve blocks are performed in different ways and for
different areas of pain, including rectal pain, kidney pain, abdominal pain
and pelvic pain.
- Neuraxial (epidural or intrathecal) nerve blocks can be quite
effective for most type of cancer pain that are not responsive to
conventional opioid administration. It allows delivery of much reduced dose
of opioids directly into the central nervous system, consequently,
maximizing analgesic control and minimizing systemic side effects of the
opioids. Most patients will undergo a trial evaluation for intrathecal
opioid delivery. After the trial, patient can decide if a permanent implant
of the infusion pump would be appropriate for his/her pain control.
Spinal Cord Stimulator. Very effective means of treating intractable
pain non-responsive to pharmacologic and/or surgical modalities. Using electrode
leads implanted into the epidural space connected to a impulse generator that is
implanted under the gluteal fat pad to replace the painful sensation with a mild
gentle tingling sensation.
Peripheral Nerve Stimulator. Similar concept as the spinal cord
stimulator, but targeting to a specific peripheral nerve.
Vertebroplasty/ Kyphoplasty. Minimally invasive procedure performed
to stabilize vertebral compression fractures and pain relieve by injecting
cements into the fracture through the skin into the vertebra body using a
needle.
Surgery
In cases where pain proves intractable, or difficult to treat, an operation
may be performed to sever the nerves transmitting the pain signals. This is
considered a treatment of last resort, since it can cause numbness or loss of
motor and/ or sensory function.